PCORnet is a national resource, funded by PCORI®, that enables insights from high-quality health data, patient partnership, and research expertise to deliver fast, trustworthy answers that advance health outcomes.

Latest News

Mark your Calendar! PCORI to Announce New Funding Opportunities for PCORnet® Studies

On April 1, PCORI will release the Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) to support high-quality patient-centered comparative clinical effectiveness research (CER). Category 3 supports PCORnet® Studies with direct costs of up to $12 million.

Featured Resource

PCORnet® Playbook

Researchers who partner with PCORnet® have access to unique representative health data, research expertise, and patient insights. Whether you are a new or an experienced researcher, the PCORnet® Playbook is your go-to guide for navigating the PCORnet infrastructure, tapping into expert support, and integrating patient perspectives into your research from the start.

Featured Research

Research Highlights Illustrate Power of PCORnet®

Learn how researchers are using PCORnet to improve patient outcomes by fueling the kind of large-scale research needed to:

Featured Network

PEDSnet

Across its founding institutions, PEDSnet, a pediatric PCORnet® Clinical Research Network, has created a longitudinal data resource that dates back to 2009, cutting across all pediatric diseases, and including all pediatric specialties.

Check out this webinar on PEDSnet’s Family and Youth Research Education Program (FYREworks).

Special Journal Supplement

A February 2026 PCORI-sponsored supplement of the journal Medical Care looks at the scope and scale of PCORnet. The 19 peer-reviewed open-access articles demonstrate the robust scientific value of PCORnet in accelerating patient-centered comparative clinical effectiveness research.

View the collection.

Events

Wednesday, April 22
12-1 pm (ET)

Join us for the webinar, Empowering Multi-Site Studies via Federated Learning Using Privacy-Preserving Distributed Algorithms (PDA).

Learn more.


Wednesday, May 6
12-1 pm (ET)

Join us for the webinar, Datavant Collaboration: Privacy-Preserving Record Linkage and Network Enablement.

Learn more.

Tools to Speed Study Start-up

Conduct patient-centered comparative clinical effectiveness research more efficiently by addressing some of the most time-consuming, costly, and difficult aspects of study start-up.