PCORnet is a national resource, funded by PCORI®, that enables insights from high-quality health data, patient partnership, and research expertise to deliver fast, trustworthy answers that advance health outcomes.
Research Powered by PCORnet® Illustrates How Partnerships Help Make Sense of Real-World Data
Research built on real-world data — information generated during routine healthcare, such as electronic health record (EHR) and claims data — can help answer questions that are often out of reach for traditional clinical trials. However, these data often require additional context to fully understand what they mean for healthcare decisions.
PCORnet® Playbook
Researchers who partner with PCORnet® have access to unique representative health data, research expertise, and patient insights. Whether you are a new or an experienced researcher, the PCORnet® Playbook is your go-to guide for navigating the PCORnet infrastructure, tapping into expert support, and integrating patient perspectives into your research from the start.
Research Highlights Illustrate Power of PCORnet®
Learn how researchers are using PCORnet to improve patient outcomes by fueling the kind of large-scale research needed to:
- Understand how different metabolic pathways interact
- Answer key questions in cardiovascular research
- Solve challenges in nephrology research
- Explore approaches to pediatric research
- Surface answers with rare disease research
REACHnet
REACHnet, a PCORnet® Clinical Research Network, includes electronic health record data for nearly 5 million patients (2023 data) from partner health systems in Louisiana, Texas and California. Its mission is to enable the conduct of multi-site research with enhanced efficiency in real-world healthcare delivery systems. REACHnet offers linkage with claims data through partnerships with Blue Cross Blue Shield of Louisiana, Humana, and Louisiana Medicaid.
Check out REACHnet's Patient Partner Recruitment & Selection Toolkit
Special Journal Supplement
A PCORI-sponsored supplement of the journal Medical Care provides peer-reviewed open-access articles that demonstrate the robust scientific value of PCORnet in accelerating patient-centered comparative clinical effectiveness research.
Event
Lessons Learned from a Community Engagement Project in Sickle Cell Disease
August 11, 2026
12 noon – 1 pm (ET)
Tools to Speed Study Start-up
Conduct patient-centered comparative clinical effectiveness research more efficiently by addressing some of the most time-consuming, costly, and difficult aspects of study start-up.