PCORnet is a national resource, funded by PCORI®, that enables insights from high-quality health data, patient partnership, and research expertise to deliver fast, trustworthy answers that advance health outcomes.

Latest News

PCORnet® Resources Are Advancing Rare Disease Research

By leveraging the real-world data resources, patient-informed insights, and the national-scale infrastructure of PCORnet®, investigators are overcoming longstanding challenges in rare disease research. Historically, research in rare health conditions has been limited by small, geographically dispersed patient populations and gaps in natural history data.

Featured Resource

PCORnet® Playbook

Researchers who partner with PCORnet® have access to unique representative health data, research expertise, and patient insights. Whether you are a new or an experienced researcher, the PCORnet® Playbook is your go-to guide for navigating the PCORnet infrastructure, tapping into expert support, and integrating patient perspectives into your research from the start.

Featured Research

Research Highlights Illustrate Power of PCORnet®

Learn how researchers are using PCORnet to improve patient outcomes by fueling the kind of large-scale research needed to:

Featured Network

REACHnet

REACHnet, a PCORnet® Clinical Research Network, includes electronic health record data for nearly 5 million patients (2023 data) from partner health systems in Louisiana, Texas and California. Its mission is to enable the conduct of multi-site research with enhanced efficiency in real-world healthcare delivery systems. REACHnet offers linkage with claims data through partnerships with Blue Cross Blue Shield of Louisiana, Humana, and Louisiana Medicaid.

Check out REACHnet's Patient Partner Recruitment & Selection Toolkit

Special Journal Supplement

A PCORI-sponsored supplement of the journal Medical Care looks at the scope and scale of PCORnet. The 19 peer-reviewed open-access articles demonstrate the robust scientific value of PCORnet in accelerating patient-centered comparative clinical effectiveness research.

View the collection.

Tools to Speed Study Start-up

Conduct patient-centered comparative clinical effectiveness research more efficiently by addressing some of the most time-consuming, costly, and difficult aspects of study start-up.